A minimum of 275  words, not including references
Citations: At least one high-level scholarly reference in APA from within the last 5 years

A 65 year old male presents with a painful left finger unable to bend and is significantly swollen.  He has a history of osteoarthritis.

OA is a disease of articular cartilage and subchondial bone in diarthrodial joints.  Explain this.
What is the role osteophytes in OA?
How do NASAIDS affect  OA?
How does weight loss affect OA?

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